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Treatment For Erectile Dysfunction

  • Treatment For Erectile Dysfunction

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    Treatment For Erectile Dysfunction

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    Erectile dysfunction (ED) is a condition in which a man regularly finds it difficult to get or keep a firm erection. ED can be caused by psychological, physical, and medical reasons. This article.


    Erectile dysfunction (ED) is the inability to achieve or maintain an erection firm enough for sexual activity. ED, also referred to as impotence, may involve the total inability to achieve an erection, or only brief erections, or not being able to reliably get an erection.


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    Journal List Ther Adv Urol v.
    I Copyright The Author(s), 2013 This article has been cited by other articles in PMC. Abstract Low-intensity extracorporeal shock wave therapy (LI-ESWT) is a novel modality that has recently been developed for treating erectile dysfunction (ED). Unlike other current treatment options for ED, all of which are palliative in nature, LI-ESWT is unique in that it aims to restore the erectile mechanism in order to enable natural or spontaneous erections.
    Results from basic science experiments have provided evidence that LI-ESWT induces cellular microtrauma, which in turn stimulates the release of angiogenic factors and the subsequent neovascularization of the treated tissue.
    Extracorporeal shock wave therapy (ESWT) has been clinically investigated and applied in several medical fields with various degrees of success.
    High-intensity shock wave therapy is used for lithotripsy because of its focused mechanical destructive nature, and medium-intensity shock waves have been shown to have anti-inflammatory properties and are used for treating a wide array of orthopedic conditions, such as non-union fractures, tendonitis, and bursitis.
    In contrast, LI-ESWT has angiogenetic properties and is therefore used in the management of chronic wounds, peripheral neuropathy, and in cardiac neovascularization.
    As a result of these characteristics we initiated a series of experiments evaluating the effect of LI-ESWT on the cavernosal tissue of patients with vasculogenic ED. The results of our studies, which also included a double-blind randomized control trial, confirm that LI-ESWT generates a significant clinical improvement of erectile function and a significant improvement in penile hemodynamics without any adverse effects.
    Although further extensive research is needed, LI-ESWT may create a new standard of care for men with vasculogenic ED. Keywords: erectile dysfunction, male impotence, shockwaves, therapy Introduction The current nonsurgical treatment modalities in the management of erectile dysfunction (ED) mainly consist of oral phosphodiesterase type 5 inhibitors (PDE5is) and/or intracavernosal injections of vasodilating agents.

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    These treatments are very effective and are reasonably safe with rare unwanted or adverse effects.
    However, they all share the same major drawback: they do not alter the underlying pathophysiology of the erectile mechanism.
    These treatments are usually taken on demand, prior to the sexual act, and their effect is essentially time limited.
    Although daily administration of a PDE5i instead of on-demand treatment does address some of these problems, it still does not modify the pathophysiology of the erectile process.
    Moreover, the evidence that its effect on the erectile tissue is long-lasting is very limited.
    Presently, only a small number of men with ED can be offered treatment that would restore their spontaneous erectile function.
    This group includes those who would benefit from various lifestyle or drug regimen modifications, those who can be treated for relevant endocrine disorders, or those with vasculogenic ED who would benefit from microvascular surgery.
    Recently, data from several studies have accumulated that this goal could probably be met by low-intensity extracorporeal shockwave therapy (LI-ESWT) of the corpora cavernosa.
    This review intends to summarize the scientific background underlying the effect of this energy as well as recent clinical evidence of its effect in patients with vasculogenic ED. Background Shockwaves (SWs) are acoustic waves that carry energy and when propagating through a medium, can be targeted and focused noninvasively to affect a distant selected anatomical region.

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